Picrorhiza kurroa – Kutki

Literatúra

Thomas M, et al. AKL1, a botanical mixture for the treatment of asthma: a randomised, double-blind, placebo-controlled, cross-over study. BMC Pulm Med. (2007)
Keche Y, Badar V, Hardas M. Efficacy and safety of livwin (polyherbal formulation) in patients with acute viral hepatitis: A randomized double-blind placebo-controlled clinical trial. Int J Ayurveda Res. (2010)
[No authors listed. Picrorhiza kurroa. Monograph. Altern Med Rev. (2001)
Upadhyay D, et al. Comparative pharmacokinetic profiles of picrosides I and II from kutkin, Picrorhiza kurroa extract and its formulation in rats. Fitoterapia. (2013)
Tiwari SS, et al. TLC densitometric quantification of picrosides (picroside-I and picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora and their antioxidant studies. Biomed Chromatogr. (2012)
Basu K, Dasgupta B, Ghosal S. Structure of kutkin, the bitter glucoside of Picrorhiza kurroa Royle ex Benth. J Org Chem. (1970)
Kumar V, et al. A Proposed Biosynthetic Pathway of Picrosides Linked through the Detection of Biochemical Intermediates in the Endangered Medicinal Herb Picrorhiza kurroa. Phytochem Anal. (2013)
Philippens IH, et al. Oral treatment with the NADPH oxidase antagonist apocynin mitigates clinical and pathological features of parkinsonism in the MPTP marmoset model. J Neuroimmune Pharmacol. (2013)
Dorsch W, et al. Antiasthmatic effects of Picrorhiza kurroa: androsin prevents allergen- and PAF-induced bronchial obstruction in guinea pigs. Int Arch Allergy Appl Immunol. (1991)
Stuppner H, Wagner H. New cucurbitacin glycosides from Picrorhiza kurrooa. Planta Med. (1989)
Vaidya AB, et al. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent–experimental & clinical studies. J Postgrad Med. (1996)
Zhang DK, et al. A Picrorhiza kurroa derivative, picroliv, attenuates the development of dextran-sulfate-sodium-induced colitis in mice. Mediators Inflamm. (2012)
Rastogi R, Srivastava AK, Rastogi AK. Long term effect of aflatoxin B(1) on lipid peroxidation in rat liver and kidney: effect of picroliv and silymarin. Phytother Res. (2001)
Transformation of aucubin to new pyridine monoterpene alkaloids, aucubinines A and B, by human intestinal bacteria.
Wang CH, et al. Pharmacokinetics and tissue distribution of gentiopicroside following oral and intravenous administration in mice. Eur J Drug Metab Pharmacokinet. (2004)
Park EJ, et al. Pharmacokinetics of verproside after intravenous and oral administration in rats. Arch Pharm Res. (2009)
Li HL, et al. Determination of the plasma pharmacokinetic and tissue distributions of swertiamarin in rats by liquid chromatography with tandem mass spectrometry. Arzneimittelforschung. (2012)
Li T, et al. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs. Xenobiotica. (2011)
Lee HS, Yoo CB, Ku SK. Hypolipemic effect of water extracts of Picrorrhiza kurroa in high fat diet treated mouse. Fitoterapia. (2006)
Lee HS, Ahn HC, Ku SK. Hypolipemic effect of water extracts of Picrorrhiza rhizoma in PX-407 induced hyperlipemic ICR mouse model with hepatoprotective effects: a prevention study. J Ethnopharmacol. (2006)
Husain GM, Singh PN, Kumar V. Antidiabetic activity of standardized extract of Picrorhiza kurroa in rat model of NIDDM. Drug Discov Ther. (2009)
Simons JM, et al. Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils. Free Radic Biol Med. (1990)
Gao HM, et al. Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson’s disease. FASEB J. (2003)
Chamorro G, et al. Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Nutr Neurosci. (2006)
Hussain A, et al. Protective effects of Picrorhiza kurroa on cyclophosphamide-induced immunosuppression in mice. Pharmacognosy Res. (2013)
Dorsch W, Wagner H. New antiasthmatic drugs from traditional medicine. Int Arch Allergy Appl Immunol. (1991)
Antarkar DS, et al. A double-blind clinical trial of Arogya-wardhani–an ayurvedic drug–in acute viral hepatitis. Indian J Med Res. (1980)
Rastogi R, Srivastava AK, Rastogi AK. Biochemical changes induced in liver and serum of aflatoxin B1-treated male wistar rats: preventive effect of picroliv. Pharmacol Toxicol. (2001)
Rastogi R, et al. Hepatocurative effect of picroliv and silymarin against aflatoxin B1 induced hepatotoxicity in rats. Planta Med. (2000)
Dwivedi Y, et al. Picroliv protects against aflatoxin B1 acute hepatotoxicity in rats. Pharmacol Res. (1993)
Saraswat B, et al. Protective effect of picroliv, active constituent of Picrorhiza kurrooa, against oxytetracycline induced hepatic damage. Indian J Exp Biol. (1997)
Santra A, et al. Prevention of carbon tetrachloride-induced hepatic injury in mice by Picrorhiza kurrooa. Indian J Gastroenterol. (1998)
Girish C, Pradhan SC. Hepatoprotective activities of picroliv, curcumin, and ellagic acid compared to silymarin on carbon-tetrachloride-induced liver toxicity in mice. J Pharmacol Pharmacother. (2012)
Dwivedi Y, et al. Picroliv affords protection against thioacetamide-induced hepatic damage in rats. Planta Med. (1991)
Girish C, et al. Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice. Fundam Clin Pharmacol. (2009)
Shukla B, et al. Choleretic effect of picroliv, the hepatoprotective principle of Picrorhiza kurroa. Planta Med. (1991)
Yadav N, Khandelwal S. Effect of Picroliv on cadmium-induced hepatic and renal damage in the rat. Hum Exp Toxicol. (2006)
Yadav N, Khandelwal S. Therapeutic efficacy of Picroliv in chronic cadmium toxicity. Food Chem Toxicol. (2009)
Singh AK, et al. Picroliv preconditioning protects the rat liver against ischemia-reperfusion injury. Eur J Pharmacol. (2000)
Effect of picroliv on antioxidant-system in liver of rats, after partial hepatectomy.
Dwivedi Y, et al. Picroliv protects against monocrotaline-induced hepatic damage in rats. Pharmacol Res. (1991)
Vivekanandan P, et al. Protective effect of picroliv against hydrazine-induced hyperlipidemia and hepatic steatosis in rats. Drug Chem Toxicol. (2007)
Dwivedi Y, et al. Picroliv and its components kutkoside and picroside I protect liver against galactosamine-induced damage in rats. Pharmacol Toxicol. (1992)
Rastogi R, et al. Picroliv protects against alcohol-induced chronic hepatotoxicity in rats. Planta Med. (1996)
Floersheim GL, et al. Protection against Amanita phalloides by the iridoid glycoside mixture of Picrorhiza kurroa (kutkin). Agents Actions. (1990)
Saraswat B, et al. Ex vivo and in vivo investigations of picroliv from Picrorhiza kurroa in an alcohol intoxication model in rats. J Ethnopharmacol. (1999)
Saraswat B, et al. Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis. Indian J Exp Biol. (1993)
Shetty SN, et al. A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease. J Ayurveda Integr Med. (2010)
Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg. (1998)
Ogata H, Hibi T. Cytokine and anti-cytokine therapies for inflammatory bowel disease. Curr Pharm Des. (2003)
Xiang JY, et al. Amelioration of murine dextran sulfate sodium-induced colitis by nuclear factor-kappaB decoy oligonucleotides. Am J Surg. (2009)
Jobin C, Sartor RB. NF-kappaB signaling proteins as therapeutic targets for inflammatory bowel diseases. Inflamm Bowel Dis. (2000)
Yadav N, Khandelwal S. Effect of Picroliv on cadmium induced testicular damage in rat. Food Chem Toxicol. (2008)
Yadav N, et al. Prevention of acute cadmium toxicity by Picroliv. Hum Exp Toxicol. (2005)
Bedi KL, et al. Picrorhiza kurroa, an ayurvedic herb, may potentiate photochemotherapy in vitiligo. J Ethnopharmacol. (1989)