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Literatúra
- Pescosolido N, Librando A. Oral administration of an association of forskolin, rutin and vitamins B1 and B2 potentiates the hypotonising effects of pharmacological treatments in POAG patients. Clin Ter. (2010)
- Oral Administration of Forskolin and Rutin Contributes to Reduce Intraocular Pressure and Improve PERG (Pattern Electroretinogram) Amplitude in Glaucomatous Patients.
- Vetrugno M1, et al. Oral administration of forskolin and rutin contributes to intraocular pressure control in primary open angle glaucoma patients under maximum tolerated medical therapy. J Ocul Pharmacol Ther. (2012)
- Agarwal KC, Parks RE Jr. Forskolin: a potential antimetastatic agent. Int J Cancer. (1983)
- Pharmacognostic Evaluation of Coleus forskohlii.
- Rosmarinic acid, scutellarein 4′-methyl ether 7-O-glucuronide and (16S)-coleon E are the main compounds responsible for the antiacetylcholinesterase and antioxidant activity in herbal tea of Plectranthus barbatus (“falso boldo”).
- Wang YQ, et al. Studies on the chemical constituents of Coleus forskohlii. Zhong Yao Cai. (2009)
- Bodiwala HS, et al. Anti-HIV diterpenes from Coleus forskohlii. Nat Prod Commun. (2009)
- Yang QR, et al. Three new diterpenoids from Coleus forskohlii Briq. J Asian Nat Prod Res. (2006)
- Shen YH, Xu YL. Two new diterpenoids from Coleus forskohlii. J Asian Nat Prod Res. (2005)
- Alasbahi RH, Melzig MF. Forskolin and derivatives as tools for studying the role of cAMP. Pharmazie. (2012)
- Shan Y, et al. Diterpenes from Coleus forskohlii (WILLD.) BRIQ. (Labiatae). Chem Pharm Bull (Tokyo). (2008)
- Shan Y, et al. Two minor diterpene glycosides and an eudesman sesquiterpene from Coleus forskohlii. Chem Pharm Bull (Tokyo). (2007)
- Falé PL, et al. Function of Plectranthus barbatus herbal tea as neuronal acetylcholinesterase inhibitor. Food Funct. (2011)
- Antiacetylcholinesterase and antioxidant activities of Plectranthus barbatus tea, after in vitro gastrointestinal metabolism.
- Xu LL, et al. Studies on the chemical constituents in root of Coleus forskohlii. Zhongguo Zhong Yao Za Zhi. (2005)
- Burns TW, et al. Comparative effects of forskolin and isoproterenol on the cyclic AMP content of human adipocytes. Life Sci. (1987)
- Stability of Forskolin in Lipid Emulsions and Oil/Water Partition Coefficients.
- Iwatsubo K, Tsunematsu T, Ishikawa Y. Isoform-specific regulation of adenylyl cyclase: a potential target in future pharmacotherapy. Expert Opin Ther Targets. (2003)
- Hanoune J, Defer N. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol. (2001)
- Litosch I, et al. Forskolin as an activator of cyclic AMP accumulation and lipolysis in rat adipocytes. Mol Pharmacol. (1982)
- Burns TW, et al. Alpha-2 adrenergic activation inhibits forskolin-stimulated adenylate cyclase activity and lipolysis in human adipocytes. Life Sci. (1982)
- Costford SR, et al. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab. (2010)
- Dubey MP, et al. Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii. J Ethnopharmacol. (1981)
- Liu ZJ, et al. Intestinal Permeability of Forskolin by In Situ Single Pass Perfusion in Rats. Planta Med. (2012)
- Mante S1, Minneman KP. Caffeine inhibits forskolin-stimulated cyclic AMP accumulation in rat brain. Eur J Pharmacol. (1990)
- Mante S1, Minneman KP. Is adenosine involved in inhibition of forskolin-stimulated cyclic AMP accumulation by caffeine in rat brain. Mol Pharmacol. (1990)
- DeLapp NW1, Eckols K. Forskolin stimulation of cyclic AMP accumulation in rat brain cortex slices is markedly enhanced by endogenous adenosine. J Neurochem. (1992)
- Fredholm BB, Jonzon B, Lindström K. Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices. Naunyn Schmiedebergs Arch Pharmacol. (1986)
- Alexander SP1, et al. A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta. Br J Pharmacol. (1994)
- Alexander SP1, et al. A1 adenosine receptor inhibition of cyclic AMP formation and radioligand binding in the guinea-pig cerebral cortex. Br J Pharmacol. (1994)
- Henderson S, et al. Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women. J Int Soc Sports Nutr. (2005)
- Godard MP, Johnson BA, Richmond SR. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res. (2005)
- Jagtap M, Chandola HM, Ravishankar B. Clinical efficacy of Coleus forskohlii (Willd.) Briq. (Makandi) in hypertension of geriatric population. Ayu. (2011)
- Martin LF, et al. Alterations in adipocyte adenylate cyclase activity in morbidly obese and formerly morbidly obese humans. Surgery. (1990)
- Activation of hormone-sensitive adenylate cyclase by forskolin.
- Filippa N, et al. Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase. Mol Cell Biol. (1999)
- Forskolin refractoriness.
- Duarte T, Menezes-Rodrigues FS, Godinho RO. Contribution of the extracellular cyclic AMP- adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle. J Pharmacol Exp Ther. (2012)
- The effect of forskolin on the isometric contraction of the isolated hemidiaphragm of the rat.
- A novel role for β-adrenoceptor signalling in skeletal muscle growth, development and regeneration.
- Richmond SR, Touchberry CD, Gallagher PM. Forskolin attenuates the action of insulin on the Akt-mTOR pathway in human skeletal muscle. Appl Physiol Nutr Metab. (2009)
- Niu W, et al. Insulin sensitivity and inhibition by forskolin, dipyridamole and pentobarbital of glucose transport in three L6 muscle cell lines. Sci China C Life Sci. (2007)
- Flores-Riveros JR, et al. Cyclic AMP-induced transcriptional repression of the insulin-responsive glucose transporter (GLUT4) gene: identification of a promoter region required for down-regulation of transcription. Biochem Biophys Res Commun. (1993)
- Cooke DW, Lane MD. Transcription factor NF1 mediates repression of the GLUT4 promoter by cyclic-AMP. Biochem Biophys Res Commun. (1999)
- Viñals F, et al. Cyclic adenosine 3′,5′-monophosphate regulates GLUT4 and GLUT1 glucose transporter expression and stimulates transcriptional activity of the GLUT1 promoter in muscle cells. Endocrinology. (1997)
- Sparks LM, et al. Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes. PLoS One. (2011)
- Baar K. Involvement of PPAR gamma co-activator-1, nuclear respiratory factors 1 and 2, and PPAR alpha in the adaptive response to endurance exercise. Proc Nutr Soc. (2004)
- Hood DA. Invited Review: contractile activity-induced mitochondrial biogenesis in skeletal muscle. J Appl Physiol. (2001)
- Baar K, et al. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. (2002)
- Seldin MM, et al. Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis. J Biol Chem. (2012)
- Mulhall JP, et al. Intracavernosal forskolin: role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy. J Urol. (1997)
- Pharmacology and inotropic potential of forskolin in the human heart.
- Caprioli J, Sears M. Forskolin lowers intraocular pressure in rabbits, monkeys, and man. Lancet. (1983)
- Burstein NL, Sears ML, Mead A. Aqueous flow in human eyes is reduced by forskolin, a potent adenylate cyclase activator. Exp Eye Res. (1984)
- Head KA. Natural therapies for ocular disorders, part two: cataracts and glaucoma. Altern Med Rev. (2001)
- Goldberg JL1, et al. Retinal ganglion cells do not extend axons by default: promotion by neurotrophic signaling and electrical activity. Neuron. (2002)
- Meyer-Franke A1, et al. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron. (1995)
- Nakazawa T1, Tamai M, Mori N. Brain-derived neurotrophic factor prevents axotomized retinal ganglion cell death through MAPK and PI3K signaling pathways. Invest Ophthalmol Vis Sci. (2002)
- Chen H1, Weber AJ. Brain-derived neurotrophic factor reduces TrkB protein and mRNA in the normal retina and following optic nerve crush in adult rats. Brain Res. (2004)
- Pernet V1, Di Polo A. Synergistic action of brain-derived neurotrophic factor and lens injury promotes retinal ganglion cell survival, but leads to optic nerve dystrophy in vivo. Brain. (2006)
- Oral Administration of Forskolin and Rutin Contributes to Reduce Intraocular Pressure and Improve PERG (Pattern Electroretinogram) Amplitude in Glaucomatous Patients.
- Virgona N, et al. Coleus forskohlii extract induces hepatic cytochrome P450 enzymes in mice. Food Chem Toxicol. (2012)
- Ding X, Staudinger JL. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J Pharmacol Exp Ther. (2005)
- Valenti S, et al. In vitro acute and prolonged effects of melatonin on purified rat Leydig cell steroidogenesis and adenosine 3′,5′-monophosphate production. Endocrinology. (1995)
- Haider SG. Cell biology of Leydig cells in the testis. Int Rev Cytol. (2004)
- Payne AH, Hales DB. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev. (2004)
- Hsu CC, et al. Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis. FEBS Lett. (2003)
- Hermansen K. Forskolin, an activator of adenylate cyclase, stimulates pancreatic insulin, glucagon, and somatostatin release in the dog: studies in vitro. Endocrinology. (1985)
- De Vries GW, et al. Effect of forskolin on beta-adrenergic hyporesponsiveness in skin. Skin Pharmacol. (1988)
- Harper JF. Desensitization in rat parotid to beta-adrenergic agonists and counteracting effects of forskolin are conserved in membrane and detergent-solubilized adenylate cyclase catalyst activity. J Cyclic Nucleotide Protein Phosphor Res. (1986)
- Forskolin Potentiates Isoprenaline-Induced Glycerol Output and Local Blood Flow in Human Adipose Tissue in vivo.
- Lafontan M, Langin D. Lipolysis and lipid mobilization in human adipose tissue. Prog Lipid Res. (2009)
- Wellman GC, et al. Role of phospholamban in the modulation of arterial Ca(2+) sparks and Ca(2+)-activated K(+) channels by cAMP. Am J Physiol Cell Physiol. (2001)
- Jeffries O, et al. cAMP/PKA-dependent increases in Ca Sparks, oscillations and SR Ca stores in retinal arteriolar myocytes after exposure to vasopressin. Invest Ophthalmol Vis Sci. (2010)
- Jones SB, et al. Alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production. Proc Natl Acad Sci U S A. (1987)
- Jones SB, Bylund DB. Characterization and possible mechanisms of alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production in HT29 cells. J Biol Chem. (1988)
- [No authors listed. Coleus forskohlii. Monograph. Altern Med Rev. (2006)
- Krall JF, Jamgotchian N. Forskolin refractoriness. Exposure to the diterpene alters guanine nucleotide-dependent adenylate cyclase and calcium-uptake activity of cells cultured from the rat aorta. Biochem J. (1987)
- Barovsky K, Pedone C, Brooker G. Forskolin-stimulated cyclic AMP accumulation mediates protein synthesis-dependent refractoriness in C6-2B rat glioma cells. J Cyclic Nucleotide Protein Phosphor Res. (1983)
- Meyer BH, et al. The effects of forskolin eye drops on intra-ocular pressure. S Afr Med J. (1987)
- Greenway FL, Bray GA. Regional fat loss from the thigh in obese women after adrenergic modulation. Clin Ther. (1987)
- González-Sánchez R, et al. Forskolin versus sodium cromoglycate for prevention of asthma attacks: a single-blinded clinical trial. J Int Med Res. (2006)
- Kaik G, Witte PU. Protective effect of forskolin in acetylcholine provocation in healthy probands. Comparison of 2 doses with fenoterol and placebo. Wien Med Wochenschr. (1986)
- Badian M, et al. Effect of forskolin eyedrops on intraocular pressure in healthy males. Klin Monbl Augenheilkd. (1984)