Hodvábne aminokyseliny (Silk Amino Acids – SAA)

Pôsobí na: estetické účinky

Hodvábne aminokyseliny sú derivované z hodvábneho vlákna kukly priadky morušovej. Obsahujú peptidické zlúčeniny Sericín-S a Sericín-L (small a large). SAA sa zdajú byť veľmi vhodnými zložkami pre zachovanie zdravej pokožky, vlasov a nechtov.

Užívanie

Na stanovenie optimálnej dávky pre ľudí zatiaľ nieje dosť údajov. Vieme zatiaľ to, že ak je potrebné aby SAA boli
absorbované v čreve, tak je nutné užívať hydrolyzovanú formu. Ak je cieľom pôsobenia priamo črevo (tenké alebo hrubé), tak nie je potrebná hydrolyzovaná forma.

Medicínske upozornenie!

Literatúra

  1. Terada S, et al. Preparation of silk protein sericin as mitogenic factor for better mammalian cell culture. J Biosci Bioeng. (2005)
  2. Kato N, et al. Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity. Biosci Biotechnol Biochem. (1998)
  3. Terada S, et al. Sericin, a protein derived from silkworms, accelerates the proliferation of several mammalian cell lines including a hybridoma. Cytotechnology. (2002)
  4. Tsujimoto K, et al. Cryoprotective effect of the serine-rich repetitive sequence in silk protein sericin. J Biochem. (2001)
  5. Dugo P, et al. Characterization of the polyphenolic fraction of Morus alba leaves extracts by HPLC coupled to a hybrid IT-TOF MS system. J Sep Sci. (2009)
  6. Mooney AC, Robertson HM, Wanner KW. Neonate silkworm (Bombyx mori) larvae are attracted to mulberry (Morus alba) leaves with conspecific feeding damage. J Chem Ecol. (2009)
  7. Wang HY, et al. Isolation and bioactivities of a non-sericin component from cocoon shell silk sericin of the silkworm Bombyx mori. Food Funct. (2012)
  8. Sato W, et al. Mitogenic effect of sericin on mammalian cells. BMC Proc. (2011)
  9. Even MS, Sandusky CB, Barnard ND. Serum-free hybridoma culture: ethical, scientific and safety considerations. Trends Biotechnol. (2006)
  10. Yanagihara K, et al. Effect of the silk protein sericin on the production of adenovirus-based gene-therapy vectors. Biotechnol Appl Biochem. (2006)
  11. Shin S, et al. Silk amino acids improve physical stamina and male reproductive function of mice. Biol Pharm Bull. (2010)
  12. Tyrosine-fortified silk amino acids improve physical function of Parkinson’s disease rats.
  13. Okazaki Y, et al. Consumption of sericin reduces serum lipids, ameliorates glucose tolerance and elevates serum adiponectin in rats fed a high-fat diet. Biosci Biotechnol Biochem. (2010)
  14. Consumption of silk protein, sericin elevates intestinal absorption of zinc, iron, magnesium and calcium in rats.
  15. Okazaki Y, et al. Consumption of a resistant protein, sericin, elevates fecal immunoglobulin A, mucins, and cecal organic acids in rats fed a high-fat diet. J Nutr. (2011)
  16. Zhang YQ. Applications of natural silk protein sericin in biomaterials. Biotechnol Adv. (2002)
  17. Zhaorigetu S, Sasaki M, Kato N. Consumption of sericin suppresses colon oxidative stress and aberrant crypt foci in 1,2-dimethylhydrazine-treated rats by colon undigested sericin. J Nutr Sci Vitaminol (Tokyo). (2007)
  18. Padamwar MN, et al. Silk sericin as a moisturizer: an in vivo study. J Cosmet Dermatol. (2005)
  19. Kim H, et al. Dietary silk protein, sericin, improves epidermal hydration with increased levels of filaggrins and free amino acids in NC/Nga mice. Br J Nutr. (2012)